Structure of PDB 3a0g Chain A

Receptor sequence

>3a0gA (length=139) Species: 10141 (Cavia porcellus)

VLSAADKNNVKTTWDKIGGHAAEYVAEGLTRMFTSFPTTKTYFHHIDVSP
GSGDIKAHGKKVADALTTAVGHLDDLPTALSTLSDVHAHKLRVDPVNFKF
LNHCLLVTLAAHLGADFTPSIHASLDKFFASVSTVLTSK

3D structure

• PDB: 3a0g Crystal structure analysis of guinea pig oxyhemoglobin at 2.5 angstroms resolution
• Chain: A
• Resolution: 2.5 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	HEM	A	Y42 F43 H45 H58 L83 H87 L91 N97 F98 L136	Y42 F43 H45 H58 L83 H87 L91 N97 F98 L136
BS02	OXY	A	H58 V62	H58 V62

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0005344 oxygen carrier activity
• GO:0019825 oxygen binding
• GO:0020037 heme binding
• GO:0031720 haptoglobin binding
• GO:0043177 organic acid binding
• GO:0046872 metal ion binding

Biological Process

• GO:0015671 oxygen transport
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005833 hemoglobin complex
• GO:0031838 haptoglobin-hemoglobin complex
• GO:0072562 blood microparticle

External links

• PDB: RCSB:3a0g, PDBe:3a0g, PDBj:3a0g
• PDBsum: 3a0g
• UniProt: P01947|HBA_CAVPO Hemoglobin subunit alpha (Gene Name=HBA)