Structure of PDB 2zze Chain A

Receptor sequence
>2zzeA (length=744) Species: 53953 (Pyrococcus horikoshii) [Search protein sequence]
EFIMKTRMFEEEGWIRKKCKVCGKPFWTLDPDRETCGDPPCDEYQFIGKP
GIPRKYTLDEMREKFLRFFEKHEIYPHGRVKRYPVLPRWRDDVLLVGASI
MDFQPWVISGEADPPANPLVISQPSIRFTDIDNVGITGRHFTIFEMMAHH
AFNYPGKPIYWMDETVELAFEFFTKELKMKPEDITFKENPWAGGGNAGPA
FEVLYRGLEVATLVFMQYKKAPENAPQDQVVVIKGEKYIPMETKVVDTGY
GLERLVWMSQGTPTAYDAVLGYVVEPLKKMAGIEKIDEKILMENSRLAGM
FDIEDLGDLRYLREQVAKRVGITVEELEKAIRPYELIYAIADHTKALTFM
LADGVVPSNVKAGYLARLLIRKSIRHLRELGLEVPLSEIVALHIKELHKT
FPEFKEMEDIILEMIELEEKKYAETLRRGSDLVRREIAKLKKKGIKEIPV
EKLVTFYESHGLTPEIVKEIAEKEGVKVNIPDNFYSMVAKEAERTLVDFE
LLKDLPDTRRLYYEDPFMKEFDAKVLRVIKDWVILDATAFYPEGGGQPYD
TGVLIVNGREVKVTNVQKVGKVIIHKVEDPGAFKEGMIVHGKIDWKRRIQ
HMRHHTGTHVLMGALVRVLGRHVWQAGSQLTTDWARLDISHYKRISEEEL
KEIEMLANRIVMEDRKVTWEWLPRTTAEQKYGFRLYQGGVVPGREIRVVK
IEDWDVQACGGTHLPSTGLVGPIKILRTERIQDGVERIIFACGE
3D structure
PDB2zze The structure of alanyl-tRNA synthetase with editing domain.
ChainA
Resolution2.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.7: alanine--tRNA ligase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C20 C23 C37 C42 C19 C22 C36 C41
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004813 alanine-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0006419 alanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2zze, PDBe:2zze, PDBj:2zze
PDBsum2zze
PubMed19549823
UniProtO58035|SYA_PYRHO Alanine--tRNA ligase (Gene Name=alaS)

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