Structure of PDB 2zxr Chain A

Receptor sequence
>2zxrA (length=616) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MRDRVRWRVLSLPPLAQWREVMAALEVGPEAALAYWHRGFRRKEDLDPPL
ALLPLKGLREAAALLEEALRQGKRIRVHGDYDADGLTGTAILVRGLAALG
ADVHPFIPSDLFLTVDCGVEVIVTDHHTLVVHPALTPDLKEKPTGAGVAF
LLLWALHERLGLPPPLEYADLAAVGTIADVAPLWGWNRALVKEGLARIPA
SSWVGLRLLAEAVGYTGKAVEVAFRIAPRINAASRLGEAEKALRLLLTDD
AAEAQALVGELHRLNARRQTLEEAMLRKLLPQADPEAKAIVLLDPEGHPG
VMGIVASRILEATLRPVFLVAQGKGTVRSLAPISAVEALRSAEDLLLRYG
GHKEAAGFAMDEALFPAFKARVEAYAARFPDPVREVALLDLLPEPGLLPQ
VFRELALLEPYGEGNPEPLFLLFGAPEEARRLGEGRHLAFRLKGVRVLAW
KQGDLALPPEVEVAGLLSENAWNGHLAYEVQAVDLRKPEALEGGIAPFAY
PLPLLEALARARLGEGVYVPEDNPEGLDYAWKAGFRLLPPEEAGLWLGLP
PRPVLGRRVEVALGREARARLSAPPVLHTPEARLKALVHRRLLFAYERRH
PGLFSEALLAYWEVNR
3D structure
PDB2zxr Structure of RecJ exonuclease defines its specificity for single-stranded DNA
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A D84 D136 H160 H161 D221 D84 D116 H126 H127 D179
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004527 exonuclease activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2zxr, PDBe:2zxr, PDBj:2zxr
PDBsum2zxr
PubMed20129927
UniProtQ5SJ47|RECJ_THET8 Single-stranded-DNA-specific exonuclease RecJ (Gene Name=recJ)

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