Structure of PDB 2zxn Chain A

Receptor sequence
>2zxnA (length=240) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLV
SYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDM
SWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLM
AICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMI
QKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
3D structure
PDB2zxn A New Class of Vitamin D Analogues that Induce Structural Rearrangement of the Ligand-Binding Pocket of the Receptor
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 S252 Q255 I256 L259 K260 P412 E416 I58 K62 S72 Q75 I76 L79 K80 P232 E236
BS02 JC1 A Y143 L229 V230 S233 R270 S271 S274 W282 C284 V296 H301 Y21 L49 V50 S53 R90 S91 S94 W102 C104 V116 H121
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2zxn, PDBe:2zxn, PDBj:2zxn
PDBsum2zxn
PubMed19193059
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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