Structure of PDB 2zl9 Chain A

Receptor sequence
>2zl9A (length=238) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMPLSMLPHLADLVS
YSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMS
WDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMA
ICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQ
KLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFG
3D structure
PDB2zl9 2-Substituted-16-ene-22-thia-1alpha,25-dihydroxy-26,27-dimethyl-19-norvitamin D3 analogs: Synthesis, biological evaluation, and crystal structure
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 I256 L259 K260 P412 E416 I57 K61 I75 L78 K79 P231 E235
BS02 VDA A Y143 L223 L226 V230 S233 R270 S271 S274 W282 C284 V296 H301 H393 F418 Y21 L42 L45 V49 S52 R89 S90 S93 W101 C103 V115 H120 H212 F237
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2zl9, PDBe:2zl9, PDBj:2zl9
PDBsum2zl9
PubMed18539034
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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