Structure of PDB 2zim Chain A

Receptor sequence
>2zimA (length=260) Species: 2209 (Methanosarcina mazei) [Search protein sequence]
PALTKSQTDRLEVLLNPKDESGKPFRELESELLSRRKKDLQQIYAEEREN
YLGKLEREITRFFVDRGFLEIKSPILIPLEYIERMGIDELSKQIFRVDKN
FCLRPMLAPNLYNYLRKLDRALPDPIKIFEIGPCYRKESDGKEHLEEFTM
LNFCQMGSGCTRENLESIITDFLNHLGIDFKIVGDSCMVYGDTLDVMHGD
LELSSAVVGPIPLDREWGIDKPWIGAGFGLERLLKVKHDFKNIKRAARSE
SYYNGISTNL
3D structure
PDB2zim Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.1.1.26: pyrrolysine--tRNA(Pyl) ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YLY A M300 A302 L305 Y306 R330 E332 L339 F342 M344 N346 Y384 E396 L397 S398 S399 W417 G419 G421 G423 M106 A108 L111 Y112 R136 E138 L145 F148 M150 N152 Y190 E202 L203 S204 S205 W223 G225 G227 G229
BS02 POP A H338 E396 R426 H144 E202 R232
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
Biological Process
GO:0043039 tRNA aminoacylation

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Molecular Function
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Biological Process
External links
PDB RCSB:2zim, PDBe:2zim, PDBj:2zim
PDBsum2zim
PubMed17592110
UniProtQ8PWY1|PYLS_METMA Pyrrolysine--tRNA ligase (Gene Name=pylS)

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