Structure of PDB 2zid Chain A

Receptor sequence
>2zidA (length=536) Species: 210007 (Streptococcus mutans UA159) [Search protein sequence]
MQKHWWHKATVYQIYPKSFMDTNGDGIGDLKGITSKLDYLQKLGVMAIWL
SPVYDSPMDDNGYDIANYEAIADIFGNMADMDNLLTQAKMRGIKIIMDLV
VNHTSDEHAWFIEAREHPDSSERDYYIWCDQPNDLESIFGGSAWQYDDKS
DQYYLHFFSKKQPDLNWENANLRQKIYDMMNFWIDKGIGGFRMDVIDMIG
KIPAQHIVSNGPKLHAYLKEMNAASFGQHDLLTVGQTWGATPEIAKQYSN
PVNHELSMVFQFEHIGLQHKPEAPKWDYVKELNVPALKTIFNKWQTELEL
GQGWNSLFWNNHDLPRVLSIWGNTGKYREKSAKALAILLHLMRGTPYIYQ
GEEIGMTNYPFKDLNELDDIESLNYAKEAFTNGKSMETIMDSIRMIGRDN
ARTPMQWDASQNAGFSTADKTWLPVNPNYKDINVQAALKNSNSIFYTYQQ
LIQLRKENDWLVDADFELLPTADKVFAYLRKVREERYLIVVNVSDQEEVL
EIDVDKQETLISNTNESAALANHKLQPWDAFCIKIL
3D structure
PDB2zid Substrate recognition mechanism of alpha-1,6-glucosidic linkage hydrolyzing enzyme, dextran glucosidase from Streptococcus mutans.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D98 R192 D194 Q236 H312 D313
Catalytic site (residue number reindexed from 1) D98 R192 D194 Q236 H312 D313
Enzyme Commision number 3.2.1.70: glucan 1,6-alpha-glucosidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A F139 Q236 W238 K275 E371 R398 F139 Q236 W238 K275 E371 R398
BS02 GLC A D60 Y63 H103 F158 D194 V195 Q236 H312 D313 R398 D60 Y63 H103 F158 D194 V195 Q236 H312 D313 R398
BS03 CA A D148 D151 D148 D151
BS04 CA A D21 N23 D25 I27 D29 D21 N23 D25 I27 D29
Gene Ontology
Molecular Function
GO:0004556 alpha-amylase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0043896 glucan 1,6-alpha-glucosidase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0009313 oligosaccharide catabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2zid, PDBe:2zid, PDBj:2zid
PDBsum2zid
PubMed18395742
UniProtQ99040|DEXB_STRMU Glucan 1,6-alpha-glucosidase (Gene Name=dexB)

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