Structure of PDB 2zg1 Chain A

Receptor sequence
>2zg1A (length=208) Species: 9606 (Homo sapiens) [Search protein sequence]
VYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYWFRDGEIPYY
AEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFR
VERGRDVKYSYQQNKLNLEVTALIEKPDIHEPLESGRPTRLSCSLPGSCE
AGPPLTFSWTGNALSPLDPETTRSSELTLTPRPEDHGTNLTCQMKRQTTE
RTVQLNVS
3D structure
PDB2zg1 Structural implications of Siglec-5-mediated sialoglycan recognition
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SIA A R124 K132 Y133 S134 R100 K108 Y109 S110 PDBbind-CN: -logKd/Ki=2.10,Kd=8.0mM
External links
PDB RCSB:2zg1, PDBe:2zg1, PDBj:2zg1
PDBsum2zg1
PubMed18022638
UniProtO15389|SIGL5_HUMAN Sialic acid-binding Ig-like lectin 5 (Gene Name=SIGLEC5)

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