Structure of PDB 2zfx Chain A

Receptor sequence
>2zfxA (length=241) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLSEEQQHIIAILLDAHHKTYDPTYADFRDFRPPVRMSPLSMLPHLADLV
SYSIQKVIGFAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDM
SWDCGSQDYKYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLM
AICIVSPDRPGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMI
QKLADLRSLNEEHSKQYRSLSFQPENSMKLTPLVLEVFGNE
3D structure
PDB2zfx Structure of the ligand-binding domain of rat VDR in complex with the nonsecosteroidal vitamin D3 analogue YR301
ChainA
Resolution1.99 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 I256 P412 L413 E416 I58 K62 I76 P232 L233 E236
BS02 YR3 A L223 A227 L229 S233 I267 R270 S271 W282 V296 H301 H393 Y397 L400 L43 A47 L49 S53 I87 R90 S91 W102 V116 H121 H213 Y217 L220
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2zfx, PDBe:2zfx, PDBj:2zfx
PDBsum2zfx
PubMed18997319
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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