Structure of PDB 2zcv Chain A

Receptor sequence
>2zcvA (length=283) Species: 562 (Escherichia coli) [Search protein sequence]
MIAITGATGQLGHYVIESLMKTVPASQIVAIVRNPAKAQALAAQGITVRQ
ADYGDEAALTSALQGVEKLLLISSSEVGQRAPQHRNVINAAKAAGVKFIA
YTSLLHADTSPLGLADEHIETEKMLADSGIVYTLLRNGWYSENYLASAPA
ALEHGVFIGAAGDGKIASATRADYAAAAARVISEAGHEGKVYELAGDSAW
TLTQLAAELTKQSGKQVTYQNLSEADFAAALKSVGLPDGLADMLADSDVG
ASKGGLFDDSKTLSKLIGHPTTTLAESVSHLFN
3D structure
PDB2zcv Crystal structure of a new type of NADPH-dependent quinone oxidoreductase (QOR2) from Escherichia coli
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.6.5.2: NAD(P)H dehydrogenase (quinone).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CU A E276 H280 E276 H280
BS02 NDP A G6 T8 G9 Q10 L11 R33 Y53 S73 S74 S75 G138 W139 Y140 R171 G6 T8 G9 Q10 L11 R33 Y53 S73 S74 S75 G138 W139 Y140 R171
Gene Ontology
Molecular Function
GO:0003955 NAD(P)H dehydrogenase (quinone) activity
GO:0008753 NADPH dehydrogenase (quinone) activity
GO:0016491 oxidoreductase activity
GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0050136 NADH:ubiquinone reductase (non-electrogenic) activity
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:2zcv, PDBe:2zcv, PDBj:2zcv
PDBsum2zcv
PubMed18455185
UniProtP39315|QOR2_ECOLI Quinone oxidoreductase 2 (Gene Name=qorB)

[Back to BioLiP]