Structure of PDB 2zba Chain A

Receptor sequence

>2zbaA (length=435) Species: 5514 (Fusarium sporotrichioides)

SFDIELDIIGQQPPLLSIYTQISLVYPVSDPSQYPTIVSTLEEGLKRLSQ
TFPWVAGQVKTEGISEGNTGTSKIIPYEETPRLVVKDLRDSAPTIEGLRK
AGFPLEMFDENVVAPRKTLAIGPGPNDPKPVLLLQLNFIKGGLILTVNGQ
HGAMDMTGQDAIIRLLSKACRNESFTEEEISAMNLDRKTVVPLLENYKVG
PELDHQIAKPAKATWAFFSFTPKALSELKDAATKTLDASSKFVSTDDALS
AFIWQSTSRVRLARLDASTPTEFCRAVDMRGPMGVSSTYPGLLQNMTYHD
STVAEIANEPLGATASRLRSELNSDRLRRRTQALATYMHGLPDKSSVSLT
ADANPSSSIMLSSWAKVGCWEYDFGFGLGKPESVRRPRFEPFESLMYFMP
KKPDGEFTASISLRDEDMERLKADEEWTKYAKYIG

3D structure

• PDB: 2zba Structural and Functional Characterization of the TRI101 Trichothecene 3-O-Acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: KINETIC INSIGHTS TO COMBATING FUSARIUM HEAD BLIGHT
• Chain: A
• Resolution: 2.0 Å

Enzymatic activity

• Enzyme Commision number: 2.3.1.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	COA	A	D169 M170 K253 F266 S268 T269 D270 A300 V301 D302 Q318 R343 S386 S387 W388 K390	D155 M156 K229 F242 S244 T245 D246 A276 V277 D278 Q294 R319 S362 S363 W364 K366
BS02	ZBA	A	P24 H165 Q318 M320 T374 S386 F416 L419 Y421	P14 H151 Q294 M296 T350 S362 F392 L395 Y397
BS03	CA	A	D218 D376	D204 D352
BS04	CA	A	D218 I221 D376	D204 I207 D352

Gene Ontology

Molecular Function

• GO:0016740 transferase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:2zba, PDBe:2zba, PDBj:2zba
• PDBsum: 2zba
• PubMed: 17923480
• UniProt: O94197|TR101_FUSSP Trichothecene 3-O-acetyltransferase TRI101 (Gene Name=TRI101)