Structure of PDB 2z4j Chain A

Receptor sequence
>2z4jA (length=248) Species: 9606 (Homo sapiens) [Search protein sequence]
PIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKWAK
ALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDLVF
NEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPVDG
LKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQPIA
RELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT
3D structure
PDB2z4j Interaction between the androgen receptor and a segment of its corepressor SHP
ChainA
Resolution2.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K720 M734 Q738 M894 K50 M64 Q68 M224
BS02 DHT A L704 N705 Q711 M745 M749 F764 T877 L34 N35 Q41 M75 M79 F94 T207 BindingDB: IC50=>10000nM,EC50=6nM,Ki=0.2nM
External links
PDB RCSB:2z4j, PDBe:2z4j, PDBj:2z4j
PDBsum2z4j
PubMed18007036
UniProtP10275|ANDR_HUMAN Androgen receptor (Gene Name=AR)

[Back to BioLiP]