Structure of PDB 2yzl Chain A

Receptor sequence
>2yzlA (length=238) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence]
KLEEILKKQPLYSGKAKSIYEIDDDKVLIEFRDDITAGGAKHDVKQGKGY
LNALISSKLFEALEENGVKTHYIKYIEPRYMIAKKVEIIPIEVIVRNIAA
GSLCRRYPFEEGKELPFPIVQFDYKNDEYGDPMLNEDIAVALGLATREEL
NKIKEIALKVNEVLKKLFDEKGIILVDFKIEIGKDREGNLLVADEISPDT
MRLWDKETRDVLDKDVFRKDLGDVIAKYRIVAERLGLL
3D structure
PDB2yzl Crystal structure of phosphoribosylaminoimidazole-succinocarboxamide synthase with ADP from Methanocaldococcus jannaschii
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 6.3.2.6: phosphoribosylaminoimidazolesuccinocarboxamide synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A Y15 G17 K18 K20 I22 V90 I92 K129 E185 D198 Y12 G14 K15 K17 I19 V86 I88 K125 E181 D194
Gene Ontology
Molecular Function
GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
Biological Process
GO:0006164 purine nucleotide biosynthetic process
GO:0006189 'de novo' IMP biosynthetic process
GO:0009236 cobalamin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2yzl, PDBe:2yzl, PDBj:2yzl
PDBsum2yzl
PubMed
UniProtQ58987|PUR7_METJA Phosphoribosylaminoimidazole-succinocarboxamide synthase (Gene Name=purC)

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