Structure of PDB 2yvo Chain A

Receptor sequence
>2yvoA (length=182) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MSPWERILLEEILSEPVRLVKERVRTHTGRELTYVYRPGPVAASFVLPVT
ERGTALLVRQYRHPTGKFLLEVPAGKVDEGETPEAAARRELREEVGAEAE
TLIPLPSFHPQPSFTAVVFHPFLALKARVVTPPTLEEGELLESLELPLTE
VYALLAKGEIQDASTALTLFYAEPHLKRLGLL
3D structure
PDB2yvo Structural basis for different substrate specificities of two ADP-ribose pyrophosphatases from Thermus thermophilus HB8
ChainA
Resolution1.67 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R62 A74 E90 E94 E137
Catalytic site (residue number reindexed from 1) R62 A74 E90 E94 E137
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A E90 E94 E139 E90 E94 E139
BS02 MG A A74 E94 A74 E94
BS03 AMP A V17 G75 E90 E136 G138 E139 V17 G75 E90 E136 G138 E139
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016462 pyrophosphatase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006753 nucleoside phosphate metabolic process
GO:0019693 ribose phosphate metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:2yvo, PDBe:2yvo, PDBj:2yvo
PDBsum2yvo
PubMed18039767
UniProtQ5SJY9

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