Structure of PDB 2ysm Chain A

Receptor sequence
>2ysmA (length=111) Species: 9606 (Homo sapiens) [Search protein sequence]
GSSGSSGANCAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAGWQ
CPECKVCQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKN
CRICISGPSSG
3D structure
PDB2ysm Solution structure of the first and second PHD domain from Myeloid/lymphoid or mixed-lineage leukemia protein 3 homolog
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.364: [histone H3]-lysine(4) N-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C10 C13 H33 C36 C10 C13 H33 C36
BS02 ZN A C25 C28 C51 C54 C25 C28 C51 C54
BS03 ZN A C57 C60 H80 C83 C57 C60 H80 C83
BS04 ZN A C72 C75 C98 C101 C72 C75 C98 C101
External links
PDB RCSB:2ysm, PDBe:2ysm, PDBj:2ysm
PDBsum2ysm
PubMed
UniProtQ8NEZ4|KMT2C_HUMAN Histone-lysine N-methyltransferase 2C (Gene Name=KMT2C)

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