Structure of PDB 2yq6 Chain A

Receptor sequence
>2yq6A (length=145) Species: 9606 (Homo sapiens) [Search protein sequence]
GPLGSMSQSNRELVVDFLSYKLSQKGYSWSQMAAVKQALREAGDEFELRY
RRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALC
VESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG
3D structure
PDB2yq6 Stabilizing the Pro-Apoptotic Bimbh3 Helix (Bimsahb) Does not Necessarily Enhance Affinity or Biological Activity.
ChainA
Resolution1.799 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E96 F97 Y101 A104 L108 Q111 E129 L130 D133 N136 G138 R139 A142 Y195 E45 F46 Y50 A53 L57 Q60 E78 L79 D82 N85 G87 R88 A91 Y144
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:2yq6, PDBe:2yq6, PDBj:2yq6
PDBsum2yq6
PubMed23151250
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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