Structure of PDB 2ypb Chain A

Receptor sequence
>2ypbA (length=67) Species: 9606 (Homo sapiens) [Search protein sequence]
GPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTHPPDKKLSKNEILR
LAMKYINFLAKLLNDQE
3D structure
PDB2ypb Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
ChainA
Resolution2.87 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R189 N193 R197 N204 S224 K225 R9 N13 R17 N24 S44 K45
BS02 dna A R195 E196 R199 R15 E16 R19
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0046983 protein dimerization activity
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:2ypb, PDBe:2ypb, PDBj:2ypb
PDBsum2ypb
PubMed23831025
UniProtP17542|TAL1_HUMAN T-cell acute lymphocytic leukemia protein 1 (Gene Name=TAL1)

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