Structure of PDB 2yp4 Chain A

Receptor sequence
>2yp4A (length=491) Species: 11320 (Influenza A virus) [Search protein sequence]
NSTATLCLGHHAVPNGTIVKTITNDQIEVTNATELVQSSSTGGICDSPHQ
ILDGENCTLIDALLGDPQCDGFQNKKWDLFVERSKAYSNCYPYDVPDYAS
LRSLVASSGTLEFNNESFNWTGVTQNGTSSACKRRSNNSFFSRLNWLTHL
KFKYPALNVTMPNNEKFDKLYIWGVHHPGTDNDQISLYAQASGRITVSTK
RSQQTVIPNIGSRPRVRDIPSRISIYWTIVKPGDILLINSTGNLIAPRGY
FKIRSGKSSIMRSDAPIGKCNSECITPNGSIPNDKPFQNVNRITYGACPR
YVKQNTLKLATGMRNVPEKQTAIAGFIENGWEGMVDGWYGFRHQNSEGIG
QAADLKSTQAAINQINGKLNRLIGKTNEKFHQIEKEFSEVEGRIQDLEKY
VEDTKIDLWSYNAELLVALENQHTIDLTDSEMNKLFERTKKQLRENAEDM
GNGCFKIYHKCDNACIGSIRNGTYDHDVYRDEALNNRFQIK
3D structure
PDB2yp4 Evolution of the Receptor Binding Properties of the Influenza A(H3N2) Hemagglutinin.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A F159 S193 F152 S186
BS02 SIA A Y98 T135 S136 S137 W153 L194 S228 Y91 T128 S129 S130 W146 L187 S221
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019062 virion attachment to host cell
GO:0019064 fusion of virus membrane with host plasma membrane
GO:0039654 fusion of virus membrane with host endosome membrane
GO:0046718 symbiont entry into host cell
GO:0046761 viral budding from plasma membrane
GO:0075512 clathrin-dependent endocytosis of virus by host cell
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016324 apical plasma membrane
GO:0019031 viral envelope
GO:0020002 host cell plasma membrane
GO:0055036 virion membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2yp4, PDBe:2yp4, PDBj:2yp4
PDBsum2yp4
PubMed23236176
UniProtK7N5L2

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