Structure of PDB 2yor Chain A

Receptor sequence
>2yorA (length=324) [Search protein sequence]
PPGPLENSSAKLVNDEAHPWKPLRPGDIRGPCPGLNTLASHGYLPRNGVA
TPVQIINAVQEGLNFDNQAAVFATYAAHLVDGNLITDLLSIGRKTRLTGP
DPPPPASVGGLNEHGTFEGDASMTRGDAFFGNNHDFNETLFEQLVDYSNR
FGGGKYNLTVAGELRFKRIQDSIATNPNFSFVDFRFFTAYGETTFPANLF
VDGRRDDGQLDMDAARSFFQFSRMPDDFFRAPSPRSGTGVEVVIQAHPMQ
PGRNVGKINSYTVDPTSSDFSTPCLMYEKFVNITVKSLYPNPTVQLRKAL
NTNLDFFFQGVAAGCTQVFPYGRD
3D structure
PDB2yor Structural Basis of Substrate Conversion in a New Aromatic Peroxygenase: P450 Functionality with Benefits
ChainA
Resolution2.19 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.11.2.1: unspecific peroxygenase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 HEM A P35 C36 P37 L39 F69 A77 T78 F121 E122 G123 S126 M127 T128 R189 E196 F199 P31 C32 P33 L35 F65 A73 T74 F117 E118 G119 S122 M123 T124 R185 E192 F195
BS02 MG A E122 G123 S126 E118 G119 S122
BS03 MZ0 A F121 T192 E196 F199 F117 T188 E192 F195
BS04 BMA A Y79 D91 N307 F310 Y75 D87 N303 F306
Gene Ontology
Molecular Function
GO:0004601 peroxidase activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2yor, PDBe:2yor, PDBj:2yor
PDBsum2yor
PubMed24126915
UniProtB9W4V6|APO1_CYCAE Aromatic peroxygenase (Gene Name=APO1)

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