Structure of PDB 2ym1 Chain A

Receptor sequence

>2ym1A (length=531) Species: 2021 (Thermobifida fusca) [Search protein sequence]

RQPPEEVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGGVWYWNRY
PGARCDIESIEYCYSFSEEVLQEWNWTERYASQPEILRYINFVADKFDLR
SGITFHTTVTAAAFDEATNTWTVDTNHGDRIRARYLIMASGQLSVPQLPF
PGLKDFAGNLYHTGNWPHEPVDFSGQRVGVIGTGSSGIQVSPQIAKQAAE
LFVFQRTPHFAVPARNAPLDPEFLADLKKRYAEFREESRNTPGGTHRYQG
PKSALEVSDEELVETLERYWQEGGPDILAAYRDILRDRDANERVAEFIRN
KIRNTVRDPEVAERLVPKGYPFGTKKLILEIDYYEMFNRDNVHLVDTLSA
PIETITPRGVRTSEREYELDSLVLATGFDALTGALFKIDIRGVGNVALKE
KWAAGPRTYLGLSTAGFPNLFFIAGPGSPSALSNMLVSIEQHVEWVTDHI
AYMFKNGLTRSEAVLEKEDEWVEHVNEIADETLYPMTASWYTGANVPGKP
RVFMLYVGGFHRYRQICDEVAAKGYEGFVLT

3D structure

PDB

2ym1 Snapshots of Enzymatic Baeyer-Villiger Catalysis: Oxygen Activation and Intermediate Stabilization.

Chain

Resolution

2.28 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.14.13.92: phenylacetone monooxygenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	V22 G23 G25 S27 E46 T47 G53 V54 W55 W57 N58 C65 D66 Y72 T118 V119 S150 G151 Q152 M446 I450	V12 G13 G15 S17 E36 T37 G43 V44 W45 W47 N48 C55 D56 Y62 T108 V109 S140 G141 Q142 M435 I439
BS02	NAP	A	Y60 R64 D66 L153 P159 G193 G195 S196 S197 Q200 R217 T218 H220 K337 A386 T387 G388 W501	Y50 R54 D56 L143 P149 G182 G184 S185 S186 Q189 R206 T207 H209 K326 A375 T376 G377 W490

Gene Ontology

	Molecular Function
GO:0004497	monooxygenase activity
GO:0004499	N,N-dimethylaniline monooxygenase activity
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0033776	phenylacetone monooxygenase activity
GO:0050660	flavin adenine dinucleotide binding
GO:0050661	NADP binding

View graph for
Molecular Function

External links

PDB	RCSB:2ym1, PDBe:2ym1, PDBj:2ym1
PDBsum	2ym1
PubMed	21697090
UniProt	Q47PU3\|PAMO_THEFY Phenylacetone monooxygenase (Gene Name=pamO)

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