Structure of PDB 2ylt Chain A

Receptor sequence

>2yltA (length=531) Species: 2021 (Thermobifida fusca) [Search protein sequence]

QPPEEVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGGVWYWNRYP
GARCDIESIEYCYSFSEEVLQEWNWTERYASQPEILRYINFVADKFDLRS
GITFHTTVTAAAFDEATNTWTVDTNHGDRIRARYLIMASGQLSVPQLPNF
PGLKDFAGNLYHTGNWPHEPVDFSGQRVGVIGTGSSGIQVSPQIAKQAAE
LFVFQRTPHFAVPARNAPLDPEFLADLKKRYAEFREESRNTPGGTHRYQG
PKSALEVSDEELVETLERYWQEGGPDILAAYRDILRDRDANERVAEFIRN
KIRNTVRDPEVAERLVPKGYPFGTKRLILEIDYYEMFNRDNVHLVDTLSA
PIETITPRGVRTSEREYELDSLVLATGFDALTGALFKIDIRGVGNVALKE
KWAAGPRTYLGLSTAGFPNLFFIAGPGSPSALSNMLVSIEQHVEWVTDHI
AYMFKNGLTRSEAVLEKEDEWVEHVNEIADETLYPMTASWYTGANVPGKP
RVFMLYVGGFHRYRQICDEVAAKGYEGFVLT

3D structure

PDB

2ylt Snapshots of Enzymatic Baeyer-Villiger Catalysis: Oxygen Activation and Intermediate Stabilization.

Chain

Resolution

2.65 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.14.13.92: phenylacetone monooxygenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	V22 G23 G25 F26 S27 E46 T47 G53 V54 W55 W57 N58 C65 D66 Y72 T118 V119 S150 Q152 L153 M446 I450	V11 G12 G14 F15 S16 E35 T36 G42 V43 W44 W46 N47 C54 D55 Y61 T107 V108 S139 Q141 L142 M435 I439
BS02	NAP	A	Y60 R64 D66 L153 P159 F161 G193 G195 S196 S197 Q200 R217 T218 H220 K336 R337 A386 W501	Y49 R53 D55 L142 P148 F150 G182 G184 S185 S186 Q189 R206 T207 H209 K325 R326 A375 W490

Gene Ontology

	Molecular Function
GO:0004497	monooxygenase activity
GO:0004499	N,N-dimethylaniline monooxygenase activity
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0033776	phenylacetone monooxygenase activity
GO:0050660	flavin adenine dinucleotide binding
GO:0050661	NADP binding

View graph for
Molecular Function

External links

PDB	RCSB:2ylt, PDBe:2ylt, PDBj:2ylt
PDBsum	2ylt
PubMed	21697090
UniProt	Q47PU3\|PAMO_THEFY Phenylacetone monooxygenase (Gene Name=pamO)

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