Structure of PDB 2ylr Chain A

Receptor sequence

>2ylrA (length=533) Species: 2021 (Thermobifida fusca) [Search protein sequence]

RRQPPEEVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGGVWYWNR
YPGARCDIESIEYCYSFSEEVLQEWNWTERYASQPEILRYINFVADKFDL
RSGITFHTTVTAAAFDEATNTWTVDTNHGDRIRARYLIMASGQLSVPQLP
NFPGLKDFAGNLYHTGNWPHEPVDFSGQRVGVIGTGSSGIQVSPQIAKQA
AELFVFQRTPHFAVPARNAPLDPEFLADLKKRYAEFREESRNTPGGTHRY
QGPKSALEVSDEELVETLERYWQEGGPDILAAYRDILRDRDANERVAEFI
RNKIRNTVRDPEVAERLVPKGYPFGTKRLILEIDYYEMFNRDNVHLVDTL
SAPIETITPRGVRTSEREYELDSLVLATGFDALTGALFKIDIRGVGNVAL
KEKWAAGPRTYLGLSTAGFPNLFFIAGPGSPSALSNMLVSIEQHVEWVTD
HIAYMFKNGLTRSEAVLEKEDEWVEHVNEIADETLYPMTASWYTGANVPG
KPRVFMLYVGGFHRYRQICDEVAAKGYEGFVLT

3D structure

PDB

2ylr Snapshots of Enzymatic Baeyer-Villiger Catalysis: Oxygen Activation and Intermediate Stabilization.

Chain

Resolution

2.26 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

1.14.13.92: phenylacetone monooxygenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	V22 G23 G25 S27 E46 T47 G53 V54 W55 W57 N58 C65 D66 Y72 T118 V119 S150 G151 Q152 L153 M446 I450	V13 G14 G16 S18 E37 T38 G44 V45 W46 W48 N49 C56 D57 Y63 T109 V110 S141 G142 Q143 L144 M437 I441
BS02	NAP	A	Y60 R64 D66 L153 P159 G193 G195 S196 S197 Q200 R217 T218 H220 R337 A386 T387 G388 W501	Y51 R55 D57 L144 P150 G184 G186 S187 S188 Q191 R208 T209 H211 R328 A377 T378 G379 W492

Gene Ontology

	Molecular Function
GO:0004497	monooxygenase activity
GO:0004499	N,N-dimethylaniline monooxygenase activity
GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0033776	phenylacetone monooxygenase activity
GO:0050660	flavin adenine dinucleotide binding
GO:0050661	NADP binding

View graph for
Molecular Function

External links

PDB	RCSB:2ylr, PDBe:2ylr, PDBj:2ylr
PDBsum	2ylr
PubMed	21697090
UniProt	Q47PU3\|PAMO_THEFY Phenylacetone monooxygenase (Gene Name=pamO)

[Back to BioLiP]