Structure of PDB 2yk7 Chain A

Receptor sequence
>2yk7A (length=322) Species: 491 (Neisseria meningitidis serogroup B) [Search protein sequence]
PVNLIFCYTILQMKVAERIMAQHPGERFYVVLMSENNNEKYDYYFNQIKD
KAEWAYFFHLPYGLNKSFNFIPTMAELKVKAMLLPKVKRIYLASLEKVSI
AAFLSTYPDAEIKTFDDGTINLIQSSSYLGDEFSVNGTIKRNFARMMIGD
WSIAKTRNASDEHYTIFKGLKNIMDDGRRKMTYLPLFDASELKAGDETGG
TVRILLGSPDKEMKEISEKAAKNFNIQYVAPHPRQTYGLSGVTTLNSPYV
IEDYILREIKKNPHTRYEIYTFFSGAALTMKDFPNVHVYALKPASLPEDY
WLKPVYALFTQSGIPILTFDDK
3D structure
PDB2yk7 Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis
ChainA
Resolution2.18 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.3.6: N-acetyllactosaminide alpha-2,3-sialyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CSF A L254 G255 H280 P281 R282 V298 I299 E300 S322 L206 G207 H232 P233 R234 V250 I251 E252 S274
BS02 EDO A L59 V63 L11 V15
External links
PDB RCSB:2yk7, PDBe:2yk7, PDBj:2yk7
PDBsum2yk7
PubMed21880735
UniProtP72097|LST_NEIMB N-acetyllactosaminide alpha-2,3-sialyltransferase (Gene Name=lst)

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