Structure of PDB 2yk5 Chain A

Receptor sequence
>2yk5A (length=326) Species: 491 (Neisseria meningitidis serogroup B) [Search protein sequence]
PVNLIFCYTILQMKVAERIMAQHPGERFYVVLMSENRNEKYDYYFNQIKD
KAEWAYFFHLPYGLNKSFNFIPTMAELKVKAMLLPKVKRIYLASLEKVSI
AAFLSTYPDAEIKTFDDGTINLIQSSSYLGDEFSVNGTIKRNFARMMIGD
WSIAKTRNASDEHYTIFKGLKNIMDDGRRKMTYLPLFDASELKAGDETGG
TVRILLGSPDKEMKEISEKAAKNFNIQYVAPHPRQTYGLSGVTTLNSPYV
IEDYILREIKKNPHTRYEIYTFFSGAALTMKDFPNVHVYALKPASLPEDY
WLKPVYALFTQSGIPILTFDDKLVPR
3D structure
PDB2yk5 Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria Meningitidis
ChainA
Resolution2.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.3.6: N-acetyllactosaminide alpha-2,3-sialyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C A L254 G255 H280 P281 V298 I299 E300 S322 G323 A324 L206 G207 H232 P233 V250 I251 E252 S274 G275 A276
BS02 EDO A D164 G166 D116 G118
BS03 EDO A L293 I299 Y302 L245 I251 Y254
External links
PDB RCSB:2yk5, PDBe:2yk5, PDBj:2yk5
PDBsum2yk5
PubMed21880735
UniProtP72097|LST_NEIMB N-acetyllactosaminide alpha-2,3-sialyltransferase (Gene Name=lst)

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