Structure of PDB 2yaj Chain A

Receptor sequence
>2yajA (length=869) Species: 1548 (Clostridium scatologenes) [Search protein sequence]
DIPEAKESTQKLMDIYYTLKVTADMEAAYWYNRTWWENDGEVIEVRRAKA
VAASLSHMTPTILPYEKLVMNKTKNVRGAFPFPWVCASFFNAQAEALMNE
VDAPAENEADSVSVVGAGGGNVTESYGNVISIAKKFGMRKEEIPVLVKTS
KPWEGISVEELSNKYSKMTPGYDQFKNIMESVICMFDSFAIPQGREVINY
YMPLQYGFDGIIKLCDEKIAEVMGEAGDDGDFGMSRGYYYAAMKEITKGL
SAWCENYSKRAKYLASIETDSEIKANYEKIEEVMGNIAHKKPANFWEAIQ
MTLCCHFGVVNEDPQSGLSIGRLGQVLQPFYEKDVEDGIMTDEEVIELLE
LYRIKITCIECFASAGVSGGVLSGNTFNNLSLGGQNYDGLSAVTPLEYLI
VEAGMRNQTPQPTLSVLYDEKTPEDFLMKAASCTKLGLGYPAWMNNQTGM
NFMMRNYGPEGMDLHDARAWCLGGCLESAPGCFLPLEYNGKVTMIPGGAS
PTCGTGVHFIGMPKVLELVLTNGLDKRTGKQVYPPHNKKLDSYETMVNQW
KEYMELTTDVVNRCNNIQMDIWRKYNMPAVNSLLKPDCFKKGKHIGTMGA
RYNSCINFESCGTITFVNSLSSIKKNVFDDSKFTIEEMTDAMLNNFGFKT
AYETEVFSPDFRESTDKSTKYEKIFAACVNAPKYGNADKYADEIFKAYHY
YIYDMTHKFRSYYGKPLYLCQISVSTHGPQGFVTLATADGRLAGTTYSDG
SVSAAAGTDKNGIYAIFESATVYDHSMHQNAQMNLKLHPTAVKGINGTRK
LLDLVRAYMRKGGFHVQFNVVDSKTLRDAQLTPEKYRELMVRVAGFTQYW
CEIGKPIQDEVIYRTEYDK
3D structure
PDB2yaj Structural Basis for a Kolbe-Type Decarboxylation Catalyzed by a Glycyl Radical Enzyme.
ChainA
Resolution1.813 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) F405 G502 C503 G873
Catalytic site (residue number reindexed from 1) F377 G474 C475 G845
Enzyme Commision number 4.1.1.83: 4-hydroxyphenylacetate decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 4HP A F214 R223 S344 G345 V399 L400 F405 C503 H536 F537 E637 I750 F186 R195 S316 G317 V371 L372 F377 C475 H508 F509 E609 I722
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0043722 4-hydroxyphenylacetate decarboxylase activity
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:2yaj, PDBe:2yaj, PDBj:2yaj
PDBsum2yaj
PubMed21823587
UniProtQ38HX4|HPDL_CLOSL 4-hydroxyphenylacetate decarboxylase glycyl radical subunit (Gene Name=csdB)

[Back to BioLiP]