Structure of PDB 2y6p Chain A

Receptor sequence
>2y6pA (length=231) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
RRAVIIPARLGSTRLKEKPLKNLLGKPLIRWVVEGLVKTGERVILATDSE
RVKEVVEDLCEVFLTPSDLPSGSDRVLYVVRDLDVDLIINYQGDEPFVYE
EDIKLIFRELEKGERVVTLARKDKEAYERPEDVKVVLDREGYALYFSRSP
IPYFRKNDTFYPLKHVGIYGFRKETLMEFGAMPPSKLEQIEGLEQLRLLE
NGIKIKVLITENYYHGVDTEEDLKIVEEKLK
3D structure
PDB2y6p Evidence for a Two-Metal-Ion Mechanism in the Cytidyltransferase Kdsb, an Enzyme Involved in Lipopolysaccharide Biosynthesis.
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.38: 3-deoxy-manno-octulosonate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CTP A A9 R10 S13 T14 R15 K19 P71 S72 G73 R76 G94 A8 R9 S12 T13 R14 K18 P70 S71 G72 R75 G93
BS02 MG A D95 D219 D94 D218
Gene Ontology
Molecular Function
GO:0008690 3-deoxy-manno-octulosonate cytidylyltransferase activity
GO:0016779 nucleotidyltransferase activity
Biological Process
GO:0009103 lipopolysaccharide biosynthetic process
GO:0033468 CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:2y6p, PDBe:2y6p, PDBj:2y6p
PDBsum2y6p
PubMed21826242
UniProtO66914|KDSB_AQUAE 3-deoxy-manno-octulosonate cytidylyltransferase (Gene Name=kdsB)

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