Structure of PDB 2y4r Chain A

Receptor sequence
>2y4rA (length=270) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
LDWVDGRPAAELSVRDRGLAYGDGLFETLAVRAGTPRLLERHLARLEEGC
RRLAIPLDTAALRQELLAFCAALGDGVAKLIVTRGEGLRGYAPPAEASPR
RILSGSPRPAYPERHWQQGVRLFACRTRLAEQPLLAGLKHLNRLEQVLAR
AEWSDAGHAEGLMLDVHERVVEGVFSNLLLVLDGTLVAPDLRRCGVAGVM
RAELLERAEGIGVPLAIRDVSMAELATADEVFLCNSQFGIWPVRALDEHV
WPVGELTRKLQDQLRDDLDF
3D structure
PDB2y4r Pseudomonas Aeruginosa 4-Amino-4-Deoxychorismate Lyase: Spatial Conservation of an Active Site Tyrosine and Classification of Two Types of Enzyme.
ChainA
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F27 T29 K140 E173 V197
Catalytic site (residue number reindexed from 1) F26 T28 K139 E172 V196
Enzyme Commision number 4.1.3.38: aminodeoxychorismate lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PLP A R46 K140 S177 V197 G199 V200 N236 S237 R45 K139 S176 V196 G198 V199 N235 S236
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0008696 4-amino-4-deoxychorismate lyase activity
GO:0016829 lyase activity
GO:0030170 pyridoxal phosphate binding
Biological Process
GO:0008153 para-aminobenzoic acid biosynthetic process
GO:0046394 carboxylic acid biosynthetic process
GO:0046656 folic acid biosynthetic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2y4r, PDBe:2y4r, PDBj:2y4r
PDBsum2y4r
PubMed21935381
UniProtQ9HZN6

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