Structure of PDB 2y4g Chain A

Receptor sequence

>2y4gA (length=500) Species: 529089 (Streptomyces sp. 307-9) [Search protein sequence]

MKHIDSVAPGDIRYEDLRRGENLRFVGDPEEIHLVGSAAEIEQVLSRAVR
SGKRVAVRSGGHCYEDFVANSDVRVVMDMSRLSAVGFDEERGAFAVEAGA
TLGAVYKTLFRVWGVTLPGGACPDVGAGGHILGGGYGPLSRMHGSIVDYL
HAVEVVVVDASGDARTVIATREPSDPNHDLWWAHTGGGGGNFGVVVRYWL
RTAEADVPPEPGRLLPRPPAEVLLNTTVWPWEGLDEAAFARLVRNHGRWF
EQNSGPDSPWCDLYSVLALTRSQSGALAMTTQLDATGPDAEKRLETYLAA
VSEGVGVQPHSDTRRLPWLHSTRWPGIAGDGDMTGRAKIKAAYARRSFDD
RQIGTLYTRLTSTDYDNPAGVVALIAYGGKVNAVPADRTAVAQRDSILKI
VYVTTWEDPAQDPVHVRWIRELYRDVYADTGGVPVPGGAADGAYVNYPDV
DLADEEWNTSGVPWSELYYKDAYPRLQAVKARWDPRNVFRHALSVRVPPA

3D structure

PDB

2y4g Tirandamycin Biosynthesis is Mediated by Co-Dependent Oxidative Enzymes

Chain

Resolution

2.03 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	V57 R58 S59 G60 G61 H62 C63 Y64 V68 G120 A121 C122 V125 G126 G129 H130 Y136 G189 G190 V195 M333 Y444 N446	V57 R58 S59 G60 G61 H62 C63 Y64 V68 G120 A121 C122 V125 G126 G129 H130 Y136 G189 G190 V195 M333 Y444 N446
BS02	TIR	A	Y64 C122 D332 M333 A337 I339 V403 T405 Y447	Y64 C122 D332 M333 A337 I339 V403 T405 Y447

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0050660	flavin adenine dinucleotide binding
GO:0071949	FAD binding

View graph for
Molecular Function

External links

PDB	RCSB:2y4g, PDBe:2y4g, PDBj:2y4g
PDBsum	2y4g
PubMed	21778983
UniProt	D3Y1I2

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