Structure of PDB 2y1h Chain A

Receptor sequence
>2y1hA (length=262) Species: 9606 (Homo sapiens) [Search protein sequence]
MGVGLVDCHCHLSAPDFDRDLDDVLEKAKKANVVALVAVAEHSGEFEKIM
QLSERYNGFVLPCLGVHPVQRSVTLKDLDVALPIIENYKDRLLAIGEVGL
DFSPRFAGTGEQKEEQRQVLIRQIQLAKRLNLPVNVHSRSAGRPTINLLQ
EQGAEKVLLHAFDGRPSVAMEGVRAGYFFSIPPSIIRSGQKQKLVKQLPL
TSICLETDSPALGPEKQVRNEPWNISISAEYIAQVKGISVEEVIEVTTQN
ALKLFPKLRHLL
3D structure
PDB2y1h Crystal Structure of the Human Tatd-Domain Protein 3 (Tatdn3)
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A E107 H147 H170 E97 H137 H160
BS02 ZN A H12 H14 E107 D218 H9 H11 E97 D208
Gene Ontology
Molecular Function
GO:0004518 nuclease activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0046872 metal ion binding
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:2y1h, PDBe:2y1h, PDBj:2y1h
PDBsum2y1h
PubMed
UniProtQ17R31|TATD3_HUMAN Putative deoxyribonuclease TATDN3 (Gene Name=TATDN3)

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