Structure of PDB 2y01 Chain A

Receptor sequence
>2y01A (length=286) Species: 9103 (Meleagris gallopavo) [Search protein sequence]
AELLSQQWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITS
LACADLVVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETL
CVIAIDRYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWW
RDEDPQALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYR
EAKEQSRVMLMREHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPD
WLFVAFNWLGYANSAMNPIIYCRSPDFRKAFKRLLA
3D structure
PDB2y01 The Structural Basis for Agonist and Partial Agonist Action on a Beta1-Adrenergic Receptor
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y01 A E130 I161 T164 E98 I129 T132
BS02 Y01 A C85 W166 C53 W134
BS03 2CV A W181 D184 N204 W149 D152 N172
BS04 2CV A R205 F315 R173 F243
BS05 2CV A V160 C163 V128 C131
BS06 Y00 A W117 D121 S211 F306 F307 N329 W330 W85 D89 S179 F234 F235 N257 W258
BS07 Y01 A A206 I209 A174 I177
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004935 adrenergic receptor activity
GO:0004940 beta1-adrenergic receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007189 adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0045823 positive regulation of heart contraction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2y01, PDBe:2y01, PDBj:2y01
PDBsum2y01
PubMed21228877
UniProtP07700|ADRB1_MELGA Beta-1 adrenergic receptor (Gene Name=ADRB1)

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