Structure of PDB 2xwp Chain A

Receptor sequence
>2xwpA (length=257) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
KKALLVVSFGTSYHDTCEKNIVACERDLAASCPDRDLFRAFTSGMIIRKL
RQRDGIDIDTPLQALQKLAAQGYQDVAIQSLHIINGDEYEKIVREVQLLR
PLFTRLTLGVPLLSSHNDYVQLMQALRQQMPSLRQTEKVVFMGHGASHHA
FAAYACLDHMMTAQRFPARVGAVESYPEVDILIDSLRDEGVTGVHLMPLM
LVAGDHAINDMASDDGDSWKMRFNAAGIPATPWLSGLGENPAIRAMFVAH
LHQALNM
3D structure
PDB2xwp Evolution in a Family of Chelatases Facilitated by the Introduction of Active Site Asymmetry and Protein Oligomerization.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.99.1.3: sirohydrochlorin cobaltochelatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIR A F10 M46 H83 I84 I85 G87 D88 E89 K92 H145 G146 A147 M201 L202 V203 H207 A208 F9 M45 H82 I83 I84 G86 D87 E88 K91 H144 G145 A146 M200 L201 V202 H206 A207
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0016852 sirohydrochlorin cobaltochelatase activity
GO:0046872 metal ion binding
GO:0046906 tetrapyrrole binding
GO:0050897 cobalt ion binding
Biological Process
GO:0006779 porphyrin-containing compound biosynthetic process
GO:0009236 cobalamin biosynthetic process
GO:0019251 anaerobic cobalamin biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2xwp, PDBe:2xwp, PDBj:2xwp
PDBsum2xwp
PubMed21173279
UniProtQ05592|CBIK_SALTY Sirohydrochlorin cobaltochelatase (Gene Name=cbiK)

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