Structure of PDB 2xwl Chain A

Receptor sequence
>2xwlA (length=221) Species: 1772 (Mycolicibacterium smegmatis) [Search protein sequence]
ATVAVVPAAGSGERLRAGRPKAFVTLGGTPLLEHALSGLRASGVIDRIVI
AVPPALTDESKLVFGGEDSVIVSGGVDRTESVALALEAAGDAEFVLVHDA
ARALTPPALIARVVAALKEGHSAVVPGLAPADTIKAVDANGAVLGTPERA
GLRAVQTPQGFHADVLRRAYARATAGGVTDDASLVEQLGTPVQIVDGDPL
AFKITTPLDLVLAEAVLAHHH
3D structure
PDB2xwl Structural and Functional Studies on Mycobacterial Ispd Enzymes
ChainA
Resolution1.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.60: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CTP A P8 A9 A10 G11 G13 E14 R15 K22 V77 D78 R79 S82 D100 K204 P7 A8 A9 G10 G12 E13 R14 K21 V76 D77 R78 S81 D99 K203
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003824 catalytic activity
GO:0016779 nucleotidyltransferase activity
GO:0050518 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GO:0070567 cytidylyltransferase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0019288 isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:2xwl, PDBe:2xwl, PDBj:2xwl
PDBsum2xwl
PubMed21543842
UniProtA0R560

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