Structure of PDB 2xto Chain A

Receptor sequence
>2xtoA (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]
SELRIILVGKTGTGKSAAGNSILRKQAFESKLGSQTLTKTCSKSQGSWGN
REIVIIDTPDMFSWKDHCEALYKEVQRCYLLSAPGPHVLLLVTQLGRYTS
QDQQAAQRVKEIFGEDAMGHTIVLFTHKEDLNGGSLMDYMHDSDNKALSK
LVAACGGRICAFNNRAEGSNQDDQVKELMDCIEDLLMEKNGDHYTNGLYS
LIQRVKEFKQSLIKYMETQRSYTA
3D structure
PDB2xto Structural Basis of Oligomerization in Septin-Like Gtpase of Immunity-Associated Protein 2 (Gimap2)
ChainA
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP A G32 G34 K35 S36 A37 S50 K51 H147 E149 N183 N184 R185 G12 G14 K15 S16 A17 S30 K31 H127 E129 N163 N164 R165 PDBbind-CN: -logKd/Ki=6.20,Kd=630nM
Gene Ontology

View graph for
Molecular Function
External links
PDB RCSB:2xto, PDBe:2xto, PDBj:2xto
PDBsum2xto
PubMed21059949
UniProtQ9UG22|GIMA2_HUMAN GTPase IMAP family member 2 (Gene Name=GIMAP2)

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