Structure of PDB 2xs8 Chain A

Receptor sequence
>2xs8A (length=697) Species: 9606 (Homo sapiens) [Search protein sequence]
ATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRR
AAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDK
GSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAK
HYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFL
KATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCI
MQANAEYHQSILAKQQYYFGEEIARLQHAAELIKTVASRYDEYVNVKDFS
DKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKF
TDLFEKMVPVSVQQSLAAYNQRKADLVNRSIAQMREATTLANGVLASLNL
PAAIEDVSGDTVPQSILTKSRSVIEQGGIQTVDQLIKELPELLQRNREIL
DESLRLLDEEEATDNDLRAKFKERWQRTPSNELYKPLRAEGTNFRTVLDK
AVQADGQVKECYQSHRDTIVLLCKPEPELNAAIPSANPAKTMQGSEVVNV
LKSLLSNLDEVKKEREGLENDLKSVNFDMTSKFLTALAQDGVINEEALSV
TELDRVYGGLTTKVQESLKKQEGLLKNIQVSHQEFSKMKQSNNEANLREE
VLKNLATAYDNFVELVANLKEGTKFYNELTEILVRFQNKCSDIVFAR
3D structure
PDB2xs8 Identification and Structural Characterization of the Alix-Binding Late Domains of Sivmac239 and Sivagmtan-1.
ChainA
Resolution2.498 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V498 A505 D506 N669 E672 G673 F676 E679 V497 A504 D505 N668 E671 G672 F675 E678
Gene Ontology
Biological Process
GO:0071985 multivesicular body sorting pathway

View graph for
Biological Process
External links
PDB RCSB:2xs8, PDBe:2xs8, PDBj:2xs8
PDBsum2xs8
PubMed20962096
UniProtQ8WUM4|PDC6I_HUMAN Programmed cell death 6-interacting protein (Gene Name=PDCD6IP)

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