Structure of PDB 2xs2 Chain A

Receptor sequence
>2xs2A (length=87) Species: 10090 (Mus musculus) [Search protein sequence]
LPEGKIMPNTVFVGGIDVRMDETEIRSFFARYGSVKEVKIITDRTGVSKG
YGFVSFYNDVDVQKIVESQINFHGKKLKLGPAIRKQH
3D structure
PDB2xs2 Kinked beta-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL.
ChainA
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A F43 K70 I72 Y82 F84 K109 P112 A113 I114 R115 K116 H123 F12 K39 I41 Y51 F53 K78 P81 A82 I83 R84 K85 H87 PDBbind-CN: Kd=38.2nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding

View graph for
Molecular Function
External links
PDB RCSB:2xs2, PDBe:2xs2, PDBj:2xs2
PDBsum2xs2
PubMed22021443
UniProtQ64368|DAZL_MOUSE Deleted in azoospermia-like (Gene Name=Dazl)

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