Structure of PDB 2xro Chain A

Receptor sequence
>2xroA (length=239) Species: 303 (Pseudomonas putida) [Search protein sequence]
QVIARAASIMRALGSHPHGLSLAAIAQLVGLPRSTVQRIINALEEEFLVE
ALGPAGGFRLGPALGQLINQAQTDILSLVKPYLRSLAEELDESVSLASLA
GDKIYVLDRIVSERELRVVFPIGINVPAAATAAGKVLLAALPDETLQAAL
GEQLPVLTSNTLGRKALVKQLSEVRQSGVASDLDEHIDGVSSFATLLDTY
LGYYSLAIVMPSSRASKQSDLIKKALLQSKLNIERAIGR
3D structure
PDB2xro Crystal Structure of Ttgv in Complex with its DNA Operator Reveals a General Model for Cooperative DNA Binding of Tetrameric Gene Regulators.
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A V16 R19 P46 S48 T49 R52 V2 R5 P32 S34 T35 R38
BS02 dna A Q15 V16 S35 L36 A37 Q51 G70 F72 Q1 V2 S21 L22 A23 Q37 G56 F58
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:2xro, PDBe:2xro, PDBj:2xro
PDBsum2xro
PubMed21078819
UniProtQ93PU6|TTGV_PSEPT HTH-type transcriptional regulator TtgV (Gene Name=ttgV)

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