Structure of PDB 2xoy Chain A

Receptor sequence
>2xoyA (length=212) Species: 9606 (Homo sapiens) [Search protein sequence]
PYVVCRQCPEYRRQAAQPPHCPDYVCPLQGSHALCTCCFQPMPDRRVERE
QDPRVAPQQCAVCLQPFCHLYWGCTRTGCYGCLAPFCELNLGDKCLDGVL
NNNSYESDILKNYLATRGLTWKNMLTESLVALQRGVFLLSDYRVTGDTVL
CYCCGLRSFRELTYQYRQNIPASELPVAVTSRPDCYWGRNCRTQVKAHHA
MKFNHICEQTRF
3D structure
PDB2xoy Structural Basis of Poly(Adp-Ribose) Recognition by the Multizinc Binding Domain of Checkpoint with Forkhead-Associated and Ring Domains (Chfr).
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C428 C431 C476 H482 C5 C8 C26 H32
BS02 ZN A C485 C488 C518 C524 C35 C38 C68 C74
BS03 ZN A C487 C524 C529 C532 C37 C74 C79 C82
BS04 ZN A C510 C513 C601 C604 C60 C63 C151 C154
BS05 ZN A C635 C641 H649 H655 C185 C191 H199 H205
External links
PDB RCSB:2xoy, PDBe:2xoy, PDBj:2xoy
PDBsum2xoy
PubMed20880844
UniProtQ96EP1|CHFR_HUMAN E3 ubiquitin-protein ligase CHFR (Gene Name=CHFR)

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