Structure of PDB 2xm7 Chain A

Receptor sequence
>2xm7A (length=307) Species: 149682 (Streptomyces roseochromogenus subsp. oscitans) [Search protein sequence]
QEFDCERFRADIRATAAAIGAPIAHRLTDTVLEAFRDNFAQGATLWKTTS
QPGDQLSYSFFSRLKMDTVSRAIDAGLLDAAHPTLAVVDAWSSLYGGAPV
QSGDFDAGRGMAKTWLYFGGLRPAEDILTVPALPASVQARLKDFLALGLA
HVRFAAVDWRHHSANVYFRGKGPLDTVQFARIHALSGSTPPAAHVVEEVL
AYMPEDYCVAITLDLHSGDIERVCFYALKVPKNALPRIPTRIARFLEVAP
SHDVEECNVIGWSFGRSGDYVKAERSYTGNMAEILAGWNCFFHGEEGRDH
DLRALHQ
3D structure
PDB2xm7 Structure and Mechanism of the Magnesium-Independent Aromatic Prenyltransferase Cloq from the Clorobiocin Biosynthetic Pathway.
ChainA
Resolution2.22 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.111: 4-hydroxyphenylpyruvate 3-dimethylallyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 34H A F68 R160 C215 L235 E281 C297 F61 R153 C208 L228 E274 C290
Gene Ontology
Molecular Function
GO:0004659 prenyltransferase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
Biological Process
GO:0017000 antibiotic biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2xm7, PDBe:2xm7, PDBj:2xm7
PDBsum2xm7
PubMed20946900
UniProtQ8GHB2|CLOQ_STRRC 4-hydroxyphenylpyruvate 3-dimethylallyltransferase (Gene Name=cloQ)

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