Structure of PDB 2xi7 Chain A

Receptor sequence
>2xi7A (length=184) Species: 11577 (La Crosse virus) [Search protein sequence]
GMDYQEYQQFLARINTARDACVAKDIDVDLLMARHDYFGRELCKSLNIEY
RNDVPFIDIILDIRPEVDPLTIDAPHITPDNYLYINNVLYIIDYKVSVSN
ESSVITYDKYYELTRDISDRLSIPIEIVIIRIDPVSRDLHINSDRFKELY
PTIVVDINFNQFFDLKQLLYEKFGDDEEFLLKVA
3D structure
PDB2xi7 Bunyaviridae RNA Polymerases (L-Protein) Have an N-Terminal, Influenza-Like Endonuclease Domain, Essential for Viral CAP-Dependent Transcription.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H34 D79 D92 Y93 H35 D80 D93 Y94
BS02 MN A D52 D79 D53 D80
BS03 XI7 A H34 D52 D79 D92 K94 H35 D53 D80 D93 K95 PDBbind-CN: -logKd/Ki=5.14,Kd=7.20uM
External links
PDB RCSB:2xi7, PDBe:2xi7, PDBj:2xi7
PDBsum2xi7
PubMed20862319
UniProtA5HC98|L_BUNLC RNA-directed RNA polymerase L (Gene Name=L)

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