Structure of PDB 2xg5 Chain A

Receptor sequence
>2xg5A (length=216) Species: 562 (Escherichia coli) [Search protein sequence]
AVSLDRTRAVFDGSEKSMTLDISNDNKQLPYLAQAWIENENQEKIITGPV
IATPPVQRLEPGAKSMVRLSTTPDISKLPQDRESLFYFNLREIPPRSEKA
NVLQIALQTKIKLFYRPAAIKTRPNEVWQDQLILNKVSGGYRIENPTPYY
VTVIGLGGSEKQAEEGEFETVMLSPRSEQTVKSANYNTPYLSYINDYGGR
PVLSFICNGSRCSVKK
3D structure
PDB2xg5 Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 EC2 A P30 Y31 L32 V56 I93 P94 P95 P30 Y31 L32 V56 I93 P94 P95 MOAD: ic50=22uM
PDBbind-CN: -logKd/Ki=4.66,IC50=22uM
BS02 EC5 A L32 V56 I93 P94 P95 L32 V56 I93 P94 P95
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0043711 pilus organization
GO:0061077 chaperone-mediated protein folding
GO:0071555 cell wall organization
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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Biological Process
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Cellular Component
External links
PDB RCSB:2xg5, PDBe:2xg5, PDBj:2xg5
PDBsum2xg5
PubMed20586493
UniProtP15319|PAPD_ECOLX Chaperone protein PapD (Gene Name=papD)

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