Structure of PDB 2xg3 Chain A

Receptor sequence
>2xg3A (length=138) Species: 9606 (Homo sapiens) [Search protein sequence]
ALIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPR
FNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVA
VNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI
3D structure
PDB2xg3 Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3.
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A H158 R162 N174 W181 E184 H46 R50 N62 W69 E72 PDBbind-CN: -logKd/Ki=4.74,Kd=18.2uM
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:2xg3, PDBe:2xg3, PDBj:2xg3
PDBsum2xg3
PubMed20873837
UniProtP17931|LEG3_HUMAN Galectin-3 (Gene Name=LGALS3)

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