Structure of PDB 2xeu Chain A

Receptor sequence
>2xeuA (length=64) Species: 9606 (Homo sapiens) [Search protein sequence]
GAMVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDSLKNANTCPTC
RKKINHKRYHPIYI
3D structure
PDB2xeu Mechanism of Ubiquitylation by Dimeric Ring Ligase Rnf4
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FRU A V17 R21 Y63 I64 V17 R21 Y63 I64
BS02 ZN A C6 C9 C33 C36 C6 C9 C33 C36
BS03 ZN A C28 H30 C47 C50 C28 H30 C47 C50
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:2xeu, PDBe:2xeu, PDBj:2xeu
PDBsum2xeu
PubMed21857666
UniProtP78317|RNF4_HUMAN E3 ubiquitin-protein ligase RNF4 (Gene Name=RNF4)

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