Structure of PDB 2xat Chain A

Receptor sequence
>2xatA (length=208) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
NYFESPFRGKLLSEQVSNPNIRVGRYSYYSGYYHGHSFDDCARYLMPDRD
DVDKLVIGSFCSIGSGAAFIMAGNQGHRAEWASTFPFHFMHEEPAFAGAV
NGYQPAGDTLIGHEVWIGTEAMFMPGVRVGHGAIIGSRALVTGDVEPYAI
VGGNPARTIRKRFSDGDIQNLLEMAWWDWPLADIEAAMPLLCTGDIPALY
QHWKQRQA
3D structure
PDB2xat Structure of the hexapeptide xenobiotic acetyltransferase from Pseudomonas aeruginosa.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.28: chloramphenicol O-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CLM A P8 F9 R10 Y30 P6 F7 R8 Y28
BS02 DCA A G120 T121 G138 S139 G154 G155 I161 G118 T119 G136 S137 G152 G153 I159
Gene Ontology
Molecular Function
GO:0008811 chloramphenicol O-acetyltransferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:2xat, PDBe:2xat, PDBj:2xat
PDBsum2xat
PubMed9578552
UniProtP26841|CAT4_PSEAE Chloramphenicol acetyltransferase (Gene Name=cat)

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