Structure of PDB 2x6s Chain A

Receptor sequence
>2x6sA (length=188) Species: 11963 (Human spumaretrovirus) [Search protein sequence]
PQKPFDKFFMDYIGPLPPSQGYLYVLVVVDGMTGFTWLYPTKAPSTSATV
KSLNVLTSIAIPRVIHSDQGAAFTSSTFAEWAKERGIHLEFSTPYHPQSG
SKVERKNSDMKRLLTKLLVGRPTKWYDLLPVVQLAMNNTYSPVLKYTPHQ
LLFGIDSNTPFANQDTLDLTREEELSLLQEIRTSLYHP
3D structure
PDB2x6s Structural Studies of the Catalytic Core of the Primate Foamy Virus (Pfv-1) Integrase
ChainA
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D128 D185 D11 D68
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:2x6s, PDBe:2x6s, PDBj:2x6s
PDBsum2x6s
PubMed20693659
UniProtP14350|POL_FOAMV Pro-Pol polyprotein (Gene Name=pol)

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