Structure of PDB 2x4t Chain A

Receptor sequence
>2x4tA (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB2x4t Class I Major Histocompatibility Complexes Loaded by a Periodate Trigger.
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 E63 K66 V67 H70 T73 D77 T80 Y99 Y116 T143 K146 W147 Y159 T163 W167 Y171 Y7 E63 K66 V67 H70 T73 D77 T80 Y99 Y116 T143 K146 W147 Y159 T163 W167 Y171
External links
PDB RCSB:2x4t, PDBe:2x4t, PDBj:2x4t
PDBsum2x4t
PubMed19655751
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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