Structure of PDB 2x2i Chain A

Receptor sequence
>2x2iA (length=1025) Species: 2782 (Gracilariopsis lemaneiformis) [Search protein sequence]
TDNPDGIDYKTYDYVGVWGFSPLSNTNWFAAGSSTPGGITDWTATMNVNF
DRIDNPSITVQHPVQVQVTSYNNNSYRVRFNPDGPIRDVTRGPILKQQLD
WIRTQELSEGCDPGMTFTSEGFLTFETKDLSVIIYGNFKTRVTRKSDGKV
IMENDEVGTASSGNKCRGLMFVDRLYGNAIASVNKNFRNDAVKQEGFYGA
GEVNCKYQDTYILERTGIAMTNYNYDNLNYNQWDLRPPHHDGALNPDYYI
PMYYAAPWLIVNGCAGTSEQYSYGWFMDNVSQSYMNTGDTTWNSGQEDLA
YMGAQYGPFDQHFVYGAGGGMECVVTAFSLLQGKEFENQVLNKRSVMPPK
YVFGFFQGVFGTSSLLRAHMPAGENNISVEEIVEGYQNNNFPFEGLAVDV
DMQDNLRVFTTKGEFWTANRVGTGGDPNNRSVFEWAHDKGLVCQTNITCF
LRNDNEGQDYEVNQTLRERQLYTKNDSLTGTDFGMTDDGPSDAYIGHLDY
GGGVECDALFPDWGRPDVAEWWGNNYKKLFSIGLDFVWQDMTVPAMMPHK
IGDDINVKPDGNWPNADDPSNGQYNWKTYHPQVLVTDMRYENHGREPMVT
QRNIHAYTLCESTRKEGIVENADTLTKFRRSYIISRGGYIGNQHFGGMWV
GDNSTTSNYIQMMIANNINMNMSCLPLVGSDIGGFTSYDNENQRTPCTGD
LMVRYVQAGCLLPWFRNHYDRWIESKDHGKDYQELYMYPNEMDTLRKFVE
FRYRWQEVLYTAMYQNAAFGKPIIKAASMYNNDSNVRRAQNDHFLLGGHD
GYRILCAPVVWENSTERELYLPVLTQWYKFGPDFDTKPLEGAMNGGDRIY
NYPVPQSESPIFVREGAILPTRYTLNGENKSLNTYTDEDPLVFEVFPLGN
NRADGMCYLDDGGVTTNAEDNGKFSVVKVAAEQDGGTETITFTNDCYEYV
FGGPFYVRVRGAQSPSNIHVSSGAGSQDMKVSSATSRAALFNDGENGDFW
VDQETDSLWLKLPNVVLPDAVITIT
3D structure
PDB2x2i Crystal Structure of Alpha-1,4-Glucan Lyase, a Unique Glycoside Hydrolase Family Member with a Novel Catalytic Mechanism.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.2.13: exo-(1->4)-alpha-D-glucan lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLC A L241 Q245 H741 L228 Q232 H728
BS02 AC1 A D239 F373 D412 Y513 D553 M554 R649 W662 D665 F698 H731 D226 F360 D399 Y500 D540 M541 R636 W649 D652 F685 H718
BS03 AC1 A G32 F33 S34 S37 T39 N40 W41 G190 A192 Q318 G19 F20 S21 S24 T26 N27 W28 G177 A179 Q305
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0016829 lyase activity
GO:0030246 carbohydrate binding
GO:0047457 exo-(1,4)-alpha-D-glucan lyase activity
Biological Process
GO:0005975 carbohydrate metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:2x2i, PDBe:2x2i, PDBj:2x2i
PDBsum2x2i
PubMed23902768
UniProtQ9STC1

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