Structure of PDB 2x1e Chain A

Receptor sequence
>2x1eA (length=354) Species: 5076 (Penicillium chrysogenum) [Search protein sequence]
MLHILCQGTPFEIGYEHGSAAKAVIARSIDFAVDLIRGKTKKTDEELKQV
LSQLGRVIEERWPKYYEEIRGIAKGAERDVSEIVMLNTRTEFAYGLKAAR
DCTTAYCQLPNGALQGQNWDFFSATKENLIRLTIRQAGLPTIKFITEAGI
IGKVGFNSAGVAVNYNALHLQGLRPTGVPSHIALRIALESTSPSQAYDRI
VEQGGMAASAFIMVGNGHEAFGLEFSPTSIRKQVLDANGRMVHTNHCLLQ
HGKNEKELDPLPDSWNRHQRMEFLLDGFDGTKQAFAQLWADEDNYPFSIC
RAYEEGKSRGATLFNIIYDHARREATVRLGRPTNPDEMFVMRFDEEDERS
ALNA
3D structure
PDB2x1e Structures of an Isopenicillin N Converting Ntn-Hydrolase Reveal Different Catalytic Roles for the Active Site Residues of Precursor and Mature Enzyme.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.164: isopenicillin-N N-acyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 X1E A D121 F122 F123 L262 R302 R310 D120 F121 F122 L261 R301 R309
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0050640 isopenicillin-N N-acyltransferase activity
Biological Process
GO:0017000 antibiotic biosynthetic process
GO:0042318 penicillin biosynthetic process
Cellular Component
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2x1e, PDBe:2x1e, PDBj:2x1e
PDBsum2x1e
PubMed20223213
UniProtP15802|AATA_PENCH Isopenicillin-N N-acyltransferase (Gene Name=aatA)

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