Structure of PDB 2wzi Chain A

Receptor sequence
>2wziA (length=640) Species: 226186 (Bacteroides thetaiotaomicron VPI-5482) [Search protein sequence]
SLQPPPQQLIVQNKTIDLPAVYQLNGGEEANPHAVKVLKELLSKGMLISI
GEKGDKSVRKYSRQIPDHKEGYYLSVNEKEIVLAGNDERGTYYALQTFAQ
LLKDGKLPEVEIKDYPSVRYRGVVEGFYGTPWSHQARLSQLKFYGKNKMN
TYIYGPKDDPYHSAPNWRLPYPDKEAAQLQELVAVANENEVDFVWAIHPG
QDIKWNKEDRDLLLAKFEKMYQLGVRSFAVFFDNISGEGTNPQKQAELLN
YIDEKFAQVKPDINQLVMCPTEYNKSWSNPNGNYLTTLGDKLNPSIQIMW
TGDRVISDITRDGISWINERIKRPAYIWWNFPVSDYVRDHLLLGPVYGND
TTIAKEMSGFVTNPMEHAESSKIAIYSVASYAWNPAKYDTWQTWKDAIRT
ILPSAAEELECFAMHNSDLGPNGHGYRREESMDIQPAAERFLKAFKEGKN
YDKADFETLQYTFERMKESADILLMNTENKPLIVEITPWVHQFKLTAEMG
EEVLKMVEGRNESYFLRKYNHVKALQQQMFYIDQTSNQNPYQPGVKTATR
VIKPLIDRTFATVVKFFNQKFNAHLDATTDYMPHKMLPLQVKANRVLISP
EIELDAIYPGENIQINRLSAGLQKAPVKFVRFQFVLTIEK
3D structure
PDB2wzi Visualizing the Reaction Coordinate of an O-Glcnac Hydrolase
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.169: protein O-GlcNAcase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CA A E32 E61 D64 E29 E52 D55
BS02 5FN A G135 Y137 K166 D242 Y282 N339 V342 D344 N372 G126 Y128 K157 D233 Y273 N330 V333 D335 N363
External links
PDB RCSB:2wzi, PDBe:2wzi, PDBj:2wzi
PDBsum2wzi
PubMed20067256
UniProtQ89ZI2|OGA_BACTN O-GlcNAcase BT_4395 (Gene Name=BT_4395)

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