Structure of PDB 2wwa Chain A

Receptor sequence
>2wwaA (length=490) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MSGFRLIDIVKPILPILPEVELPFEKLPFDDKIVYTIFAGLIYLFAQFPL
VGLPKATTPNVNDPIYFLRGVFGCEPRTLLEFGLFPNISSGLILQLLAGL
KVIKVNFKIQSDRELFQSLTKVFAIVQYVILTNIFIFAGYFGDDLSVVQI
GLINFQLVGAGIFTTLLAEVIDKGFGFSSGAMIINTVVIATNLVADTFGV
SQIKVGEDDQTEAQGALINLIQGLRSKHKTFIGGIISAFNRDYLPNLTTT
IIVLAIAIIVCYLQSVRVELPIRSTRARGTNNVYPIKLLYTGCLSVLFSY
TILFYIHIFAFVLIQLVAKNEPTHIICKIMGHYENANNLLAVPTFPLSLL
APPTSFFKGVTQQPLTFITYSAFILVTGIWFADKWQAISGSSARDVALEF
KDQGITLMGRREQNVAKELNKVIPIAAVTGASVLSLITVIGESLGLKGKA
AGIVVGIAGGFSLLEVITIEYQQSGGQSALNQVLGVPGAM
3D structure
PDB2wwa Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome.
ChainA
Resolution8.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A E21 F24 I42 F48 V51 Q156 A160 F163 F175 E21 F24 I42 F48 V51 Q156 A160 F163 F175
BS02 rna A R273 S274 T275 R276 A277 R278 R410 E412 Q413 N414 V415 R273 S274 T275 R276 A277 R278 R410 E412 Q413 N414 V415
BS03 rna A T406 L407 T406 L407
Gene Ontology
Molecular Function
GO:0005048 signal sequence binding
GO:0005515 protein binding
GO:0008320 protein transmembrane transporter activity
GO:0043022 ribosome binding
Biological Process
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation
GO:0015031 protein transport
GO:0031204 post-translational protein targeting to membrane, translocation
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005784 Sec61 translocon complex
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0071261 Ssh1 translocon complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2wwa, PDBe:2wwa, PDBj:2wwa
PDBsum2wwa
PubMed19933108
UniProtP38353|SSH1_YEAST Sec sixty-one protein homolog (Gene Name=SSH1)

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