Structure of PDB 2wuh Chain A

Receptor sequence
>2wuhA (length=163) Species: 9606 (Homo sapiens) [Search protein sequence]
NPAICRYPLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEGDGAWCPE
IPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRD
GTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMN
VCMRVELYGCVWL
3D structure
PDB2wuh Crystallographic Insight Into Collagen Recognition by Discoidin Domain Receptor 2
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.1: receptor protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A D69 H110 I112 E113 L188 D44 H85 I87 E88 L163
BS02 peptide A W52 C73 R105 E113 C177 W27 C48 R80 E88 C152
External links
PDB RCSB:2wuh, PDBe:2wuh, PDBj:2wuh
PDBsum2wuh
PubMed20004161
UniProtQ16832|DDR2_HUMAN Discoidin domain-containing receptor 2 (Gene Name=DDR2)

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